Senior Scientist, I at AbbVie — Worcester, MA

Conceive and implement novel experimental approaches to answer scientific questions. Investigate, identify, develop, and optimize new methods and techniques. Contribute to project science in area of expertise. Develop productive collaborations and communications with other groups across science disciplines.

Responsibilities

• Develop recovery and purification process that utilizes clarification, chromatography, and membrane filtration technologies for monoclonal antibodies, bispecifics and antibody drug conjugates (ADC). Provide deeper understanding of process performance using appropriate experimental and modeling tools.
• Design and execute process development and characterization activities, impurity and viral clearance studies. Highly independent and productive in performing laboratory research and/or development, requiring only minimal direction from or interaction with supervisor.
• Responsible for technology transfer to pilot lab and cGMP manufacturing facilities, troubleshooting and investigation activities. Provide person-in-plant support for pilot and/or cGMP manufacturing campaigns.
• Play a key role in coming up with protein structure properties modeling and/or analytical characterization to build deep scientific understanding of protein property and its impact on manufacturability.
• Exhibit a strong motivation to implement and advance various innovative technologies (such as AI skillset, automation/highthroughput, and/or novel resins) in relevant areas across AbbVie.
• Routinely demonstrate scientific initiative and creativity in research or development activities. Capable of being a primary author of publications, presentations, regulatory documents and/or primary inventor of patents.
• Understand and adhere to corporate standards regarding code of conduct, safety, appropriate handling of materials, controlled drug and radioactive compounds, GxP compliance, and animal care where applicable
• Bachelor’s Degree or equivalent education and typically 10 years of experience, Master’s Degree or equivalent education and typically 8 years of experience, PhD and no experience necessary.
• Possess thorough theoretical and practical understanding of own scientific discipline.
• Education background in chemical engineering, biophysics, biochemistry, biochemical engineering, or biotechnology is preferred.
• Experience in areas of biophysical characterization and/or protein structure modeling is strongly preferred
• Experience in areas of purification process development is strongly preferred.
• Direct experience and/or collaboration experience in areas of biologics LC-MS is preferred
• Demonstrate excellent communication skills and specifically illustrate strong oral and written technical communications.
• Seamlessly present research outcomes to multifunctional teams
• Play a strong team player in a cross functional collaborative environment thriving for world class excellence and maintains strong working relationships with internal, global, and external collaborators.
• Demonstrated problem-solving skills and capability to overcome complex issues.
• Demonstrated success in coordinating and executing important projects to achieve business goals.
• Must have a “results-oriented” work ethic and a positive “can-do” attitude with a strong sense of urgency and self-motivated desire to achieve.

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: ​

• The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this roleat  the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on manyfactors  including  geographic location, and we may ultimately  pay more or less than the posted range. This range may be  modified in the future. ​
• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.​
• This job is eligible to  participate in our short-term incentive programs.  ​

Note: No amount of pay is  considered to be wages or compensation until such amount isearned,  vested,  and determinable. The amount and availability of  any bonus, commission, incentive, benefits, or any other form of compensation and benefits that areallocable to a   particular employee  remains in the Company's sole and absolute discretion unless and until paid and may be  modified at the Company’s sole and absolutediscretion,  consistent with applicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community.  Equal Opportunity Employer/Veterans/Disabled.

US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

https://www.abbvie.com/join-us/reasonable-accommodations.html